Recombinant DNA production of spider silk proteins
نویسندگان
چکیده
Spider dragline silk is considered to be the toughest biopolymer on Earth due to an extraordinary combination of strength and elasticity. Moreover, silks are biocompatible and biodegradable protein-based materials. Recent advances in genetic engineering make it possible to produce recombinant silks in heterologous hosts, opening up opportunities for large-scale production of recombinant silks for various biomedical and material science applications. We review the current strategies to produce recombinant spider silks.
منابع مشابه
Synthetic biology increases efficiency of Escherichia coli to produce Parawixia bistriata spider silk protein
Background Spider dragline silk is considered to be the toughest biopolymer on Earth due to an extraordinary combination of strength and elasticity. With synthetic biology it is possible to express recombinant spider silk proteins, which are characterized by a highly repetitive rich glycine and alanine sequence [1]. However, production of high molecular weight spider silk protein can be difficu...
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عنوان ژورنال:
دوره 6 شماره
صفحات -
تاریخ انتشار 2013